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Also, in vitro studies indicate that the responsiveness of pro-B cells to IL-7 is compromised in aged individuals [355], and IL-7 release from stromal cells in the bone marrow also declines with age [356], leading to reduced pro B-cell proliferation

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application of a 2 Hz train-of-four stimulus protocol using an nerve stimulator over the ulnar nerve) can be used to assist in patient management

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